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Judging by the response from this morning's data presentation, even in it's crudely premature form, I've got a dissertation project.
Now how to frame the damn question. Questions, really.
For those of you for whom it might actually mean something, the hypothesis roughly reads like so:
Helicobacter pylori infection in a mouse model promotes skewing towards a Th17-type immune response to prevent immune clearance, by blocking full development of a functional/clearing Th1-type cytokine response.
Or, a translation, stripping out most of the not-critical and rather-scary specifics:
We've got a bacterial pathogen that has evolved mechanisms to tweak its host's immune system to prevent the host from ever really clearing the bug, causing a lot of grief in the meantime.
The questions are easier to figure out from that statement, anyway.
Now how to frame the damn question. Questions, really.
For those of you for whom it might actually mean something, the hypothesis roughly reads like so:
Helicobacter pylori infection in a mouse model promotes skewing towards a Th17-type immune response to prevent immune clearance, by blocking full development of a functional/clearing Th1-type cytokine response.
Or, a translation, stripping out most of the not-critical and rather-scary specifics:
We've got a bacterial pathogen that has evolved mechanisms to tweak its host's immune system to prevent the host from ever really clearing the bug, causing a lot of grief in the meantime.
The questions are easier to figure out from that statement, anyway.
